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Importance of Immune System
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Immune System and Diseases

Immune System and Diseases

Importance of Immune System

This is a transcript of an interview with Dr. Darryl See, Director of the Institute of Longevity Medicine & Chairman of the Research Division of the American Nutraceutical Association - January 2003

Key quotes from this interview:

Dr. See: It is important to understand that there are, in the natural realm, a fair number of products that purely boost the immune system. You will see labels that say 'boosts the immune system,' 'greatly augments the immune system,' etc. This is a very dangerous concept. I want to briefly introduce you to the concept of immune modulation versus immune boosting.

Immune modulation means that the immune system is appropriately balanced to address the disease at hand, to prevent recurrence and to protect the body against disease. Because, if you just use pure immune system boosters, it has been shown by scientific studies, that the risk of autoimmune disease goes up. I don't think it takes a rocket scientist to figure that out. If you are boosting everything, then you are going to start attacking parts of your body and indeed that happens.

But, that does not happen with Transfer Factor. Transfer factors are composed of two primary populations, an immune boosting population, and an immune suppressing population. They are intelligent. They are encoded for our DNA and they are intelligent transfer factors that work together. They know when the suppressor functions should come in to play to assist with rheumatoid arthritis or some autoimmune disease. As a matter of fact, my uncle had rheumatoid arthritis. He is amazed now that six months later, he is completely free of rheumatoid symptoms whatsoever, just taking Transfer Factor and multivitamins. The Biovitamins that 4Life have available are very very excellent. I think everyone should take those as well because we are almost all deficient in vitamins and minerals as well.

This is the concept of immune modulation and there are very few immune modulators that exist. There are certainly non, absolutely zero, in the drug realm. In the non-drug realm there are only a couple. As a matter of fact, one of them is mannans, which is in Transfer Factor Plus. 4Life have covered it very nicely. And, among immune modulators, there is the strongest immune modulator, Transfer Factor Plus, that we have found so far and the second strongest is Transfer Factor itself. This is very impressive to us.

When testing, we start off with the early studies - then companies will usually come back to us and ask if we want to extend our studies and usually we do not. But, in the case of Transfer Factor, we extended into a large cancer study and the results were quite remarkable using Transfer Factor Plus. The immune system plays a huge part in prevention of cancer, in the active phase and in prevention of recurrence. And reminding you that this is the number one killer. It also has a very interesting positive effect in preventing heart disease and diabetes, again the 1,2 and 3 killers.

From Japan - the Saitama Cancer Group in the Lancet 2000, vol 356 - we know for sure now that person with decreased immune function - and that immune function is defined as NK cell function (I just wanted to make sure you know that and that is what we are studying in particular, patients that are in that category, whether it be from toxins, drugs, genetics, it does not matter, are at an increased risk of cancer, sometimes a very dramatic increased risk of cancer) - that if you increase their NK cell function, which is the primary defense of the body getting cancer - the risk of cancer goes down.

Even as a purely objective, third-party person, I cannot imagine anyone in the world not taking Transfer Factor. I could not imagine that you would not do it. Because, the effect on the immune is so remarkable, that we have not seen anything else that equals it. The protection that it gives us if we are not sick is remarkable, and if we are sick it will help because there is bound to be an immunological component on one disease. After a disease has "gone", you have to continue because diseases do recur. We have shown that as well, you must continue. This is not a statement that the FDA has evaluated, etc, I need to make that clear to you. But, from our five independent studies, this is a conclusion that we have certainly made.

The second important point is that transfer factors, since they have suppressor and booster functions, are immune modulators. Transfer factors are therapeutic in persons with autoimmune diseases because they know how to interact with each other and suppress the immune system where appropriate, and boost the immune system where appropriate in people with autoimmune disease. So it is safe in any person, even transplant patients.

I get that question a lot, with people with heart transplant or liver, are transfer factors safe? Yes they are because they are immune modulators. T-cells that are typically activated that cause rejection in tissues are not activated in autoimmune diseases and transplants, so they are perfectly safe.

There is another extremely important point I want to make. There is no way you can possibly get toxic from taking transfer factors. We have gone up to extremely high concentrations, up to the equivalent of someone taking 100 bottles of TF in a one hour period without any toxicity whatsoever. This is an ideal product for lay persons to go out and really make an impact, a positive impact, on the health crisis that we are seeing on a world-wide basis, in regard to degenerative diseases. It is safe in their hands. I am very scared of some products that are floating around in laypersons' hands that are not safe. This is another safe point to take home, you cannot hurt anyone with it. You don't have to know anything about disease. You cannot help but help them. If someone is well, you just cannot help but to help them to prevent disease.

That is why I would like everyone to have that Lancet study and to know that Lancet study to give to people. You show them two studies. One has already been pretty well circulated where I have shown that TF Plus and TF increase the immune system to unprecedented levels, and when you put that together with that study it is very easy to make the connection that the risk of cancer is going to be much lower in someone that is improving their immune system and this is a very safe easy way to do this. So, that kind of encapsulates our first study, those main points. There were other points, and we have those in for the publication, but those are the main points.

Then we did a huge study looking at cancer patients that were given up by their doctors with an average of about 5 months survival period of time. Now we are about 9 months out and we would expect statistically that about 4-5 of those patients would be barely alive, but as it turns out 16 out of the 20 patients that are taking Transfer Factor Plus are doing extremely well. They are either in remission, stable or getting better. It is a pretty remarkable study. It is a 42 page study that I sent to a very prominent cancer journal and hopefully we will get it in there. It was very carefully done. I am very excited about it. There is absolutely no doubt, based on the Japanese data that when it comes to cancer that Transfer Factors will help prevent cancer and when a person has cancer, whatever the doctor is doing, you will help that person.

If that person is getting chemo or radiation, you are not going to decrease the efficacy of that chemotherapy or radiation, or whatever, you are going to help the immune system fight that cancer because cancers release toxins that suppress the immune system. I am not going to go through all of the mechanisms, but there are actually about five ways that Transfer Factor Plus and two or three ways that Transfer Factor work to destroy cancer cells. They do not do it just by boosting the immune system. They do some pretty amazing things inside the cells too, like increase apoptosis, which is program cell death, which we want to see in diseases like cancer. So, this is our second very large study.

We have recently done another study where we looked at macrophage function. Macrophages are another type of immune cell that are not as important as NK cells, but they are important in viral infected cells, particularly in bacterially-infected cells. We found a very nice boost in macrophage cells as well. And again in levels up to that we had not seen before. This was an important nice study because we did it in a blind fashion. We were given three different products, three transfer factor or colostrum related products and we were not told which was which. And we did the test.

One was far superior to the others and that turned out to be 4Life's Transfer Factor Plus and Transfer Factor. It's very hard to argue with a blinded study. I am working on that one right now. There are two that I sent at least a month ago for publication and it is usually about an 8 week period of time. There, in the coming weeks, we are going to be talking a lot more and I will go into more detail about immune modulation, about the papers, how TF works, when to use it, when to not and those types of things.

Dr. See: I just wanted to give you an introduction today and just conclude, so we have some time to answer some questions, with a very intriguing area that I am very interested in right now, and that is in diabetes. Diabetes is the most common degenerative disease in the world right now. It is growing every year. It causes a tremendous amount of complications in the heart, kidneys, legs, nerves, and eyes and as it turns out the therapy for diabetes, insulin, is toxic to the body. Insulin causes heart disease and it is very difficult, in fact impossible, to modulate (to make sure the amount of insulin in the body is just right so that it does not have deleterious effects.)

Insulin has been shown clearly to age the body quickly, to have negative effects on the cells, heart, kidneys, etc, when it is imbalance. We are finding now, and when I went back into some old literature I was amazed, people have found this before that transfer factors do help people with diabetes. We will keep that as a subject for some other time. But I just wanted to mention it now too because you might see some pretty amazing things if you let a person stay on their insulin and oral hypoglycemics. You are not going to hurt them at all if they try some transfer factors. A warning here - they may have to go way down on their medication after about 1-3 months. We see that all of the time.

As a matter of fact, I got called to the Emergency Room twice on patients that I started Transfer Factor on because by that time I had done some insulin-receptor studies and I was thinking this just may be of some help, it certainly is going to help them prevent other chronic diseases. Then the person feels so much better that they stop looking at their glucose levels, they stop doing their finger pricks, or urines or whatever and the hospital called and their blood sugar was in the 20s-30s. It had dropped so much because of the transfer factors. I will have a lot more information about that over the next couple of months. That will be the sixth study that we will have.

Basically it's important for you to know that you have a product hat has been proven by our studies so far to be non-toxic, no drug interaction, to boost the part of the immune system that fights diseases while at the same time decreasing the part of the immune system that causes autoimmune disease and graft rejection. Combining that with the Japanese study, we have a product here that boosts the main defense against cancer to such a high degree that, although we have not had time to prove it completely in a prevention sense, TF and TF Plus are extremely important to cancer and any cancer patient. I would use them. During our last conference call, I kind of blew everybody away because everyone asked me for a list for the products that I would recommend. As it turned out, 4Life was coming out with a product called RiteStart that had the exact ingredients in the right combination that are the most effective in cancer, so I was very happy to see that.

Q: What would you start a diabetes patient on?

Dr. See: There are three products 4Life have and one product that you don't have yet, but I am talking to your scientific people, but it is a simple product you can get from a healthfood store. So, four products for diabetics. One warning: A diabetic person needs to monitor their blood sugars because the blood sugars can certainly go down. I always pick TF Plus for diabetic patients who tend to get infections. Those diabetics who are trying to stay well, just TF would be good enough, about 6 a day would be fine.

Diabetics are always deficient in Vanadium, in chromium, vit C, and vit E, and zinc in particular. Those are absolutely crucial in cellular function that lead to complications in diabetes. You cannot just pop 6 TF and get better necessarily. Three bio-multivitamins a day would be very recommendable. There is another product that is fantastic at lowering blood sugar called gynema sylvestre. 4Life have this product (Gulcoach - available in US and few other countries). The third product I know is available in Australia is alpha lipoic acid. There is a little of this in the Biovitamins, but not enough for diabetics. You need 200 mg of alpha lipoic acid. So I would go with 6 TF or TF Plus, three BioVitamins and 200 mg of alpha lipoic acid and I believe you will see some amazing things.

If things are complicated (eg diabetic neuropathy), that has to be handled a little differently, or kidney failure, already the eyes are starting to get shot, or the heart, etc. I will give you a number, I am not trying to plug the clinic, but if you call 949-645-8100 ext 3 you will get me or my partner and leave a message, we will call you back and we can set up a consultation and we can set up other products that will work in combination with those to particularly not drop the sugars, but to prevent complications. 4Life Distributors, without any risk whatsoever, can certainly go ahead and recommend TF, TF Plus, the BioVitamins and the alpha lipoic acid. These will do amazing things. That is what you can start doing right now to help your diabetic patients.

Q: Dr. Michael Woolridge, who is the Australian Federal Health Minister, is just retiring. He has been on the Federal Health Ministry for about 5 years, and here's something the stated at a national press conference on the 25th of October of this year. He said that we do have a choice in health care. It is between the vision of focusing on outcomes, focusing on managing diseases, focusing on fixing the practical problems people experience day to day in the challenges with health - or a vision focused on monolithic hospitals, that are in essence sickness - based rather than wellness-based.

Dr. See: Absolutely. In the chronic degenerative disease we've talked about, which covers most of the immunologic disease, all western medicine can really do is put bandaids on it. Those bandaids are really expensive bandaids, but it does not get down to the root of the problem.

Transfer factors bind to receptors and they increase cyclic A&P levels. We know what they do inside the cells. We are improving cellular health in the immune system and other tissues that are biochemically very sound, so you make an excellent point that we are addressing diseases now which is part of the paradigm shift from a wellness perspective, which is getting cells healthy rather than poisoning systems and just trying to control symptoms. Medicine has to head in that direction, and certainly is. But we're going to have a big fight with the systems that are already in place. But patient demand is big. When people start throwing away insulin syringes, we are not making any claims or anything, but when we start seeing cancer incidence going down, then hopefully patients are going to start driving the system.

We are seeing that just beginning in the States right now. It is going to free up so much money that is otherwise wasted and also get to the bottom line with patients to help them from a cellular level instead of just putting a bandaid on them. Shifts come hard sometimes, but this is just too important and the science is too overwhelming. We have so much objective data, you have probably just a little bit of the data that we have put out and 4Life has put out, but now with the publications I have sent out we are going to have tremendous amounts of objective data.

Q: What would you recommend for chronic fatigue syndrome?

Dr. See: I have had thousands of chronic fatigue patients. Chronic fatigue is difficult to do in 30 seconds. But I can quickly cover the important points.

1) It is a variety of diseases. So it is crucial that you get yourself an expert that can rule out testosterone deficiencies, immune deficiency. I would say about 60% of chronic fatigue patients have natural killer deficiency, about 40% have testosterone deficiency, about 30% have pregnenalone deficiency, about 40% have Mycoplasma incognitos superinfection which mannans works absolutely fantastic against that. It is unbelievable. So, first thing to do is to realize it is not one disease. You have to get into an expert and get the right testing done so the expert can get the right testing done to be led in the right direction to give that person the very best combination.

2) The second point to make is this. All chronic fatigue syndrome patients by definition have some kind of immune deficiency, so you cannot help but to do them good to give them transfer factor and for reasons that I will go into later, I would give CFS patients just regular transfer factor, not TF Plus, unless they have Mycoplasma incognitios. I know that is kind of complicated. TF by itself unless they have Mycoplasma, then TF Plus. It took 12 years for me to figure that out but it really holds true. Make sure you get the right workup and transfer factor is going to be helpful no matter what.

3) Every chronic fatigue syndrome patient is vitamin deficient, across the board. The always have mineral deficiency - always have malnutrition. So the BioVitamins help that for sure. All females with chronic fatigue have hormonal deficiency and soy isoflavones, which is in th 4Life Genestein Plus, are extremely beneficial in the hormonal deficiency. If you are a male take the multivitamin, the TF or TF Plus, the BioEFA, and if you are female also take the BioGenistein and then based on the lab results you will probably end up on some other things as well.

In a nutshell, that is a start to handling chronic fatigue syndrome.

 

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