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In ordinary
conversation, nearly any mood with some
element of sadness may be called
"depressed". However, for depression to be
termed
clinical depression it must reach
criteria which are generally accepted by
clinicians; it is more than just a temporary
state of sadness. Generally, when
depression symptoms
last two weeks or more, and are so severe
that they interfere with daily living, one
can be said to be suffering from
clinical
depression. Using DSM-IV-TR terminology,
someone with a major depressive disorder
can, by definition, be said to be suffering
from clinical depression. True
clinical
depression is distinguished from non-organic
illnesses that mimic it, such as caffeinism.
Clinical
depression affects about 16% of the
population on at least one occasion in their
lives. The mean age of onset, from a number
of studies, is in the late 20s.
About 2
times as many females as males report or
receive treatment for clinical depression,
though this imbalance is shrinking over the
course of recent history;
this
difference
seems to
completely
disappear
after
the age
of 50 -
55, when
most
females
have
undergone
the end
of
menopause.
Clinical depression is
currently the leading cause of disability in
the US as well as other countries, and is
expected to become the second leading cause
of disability worldwide (after
heart
disease) by the year 2020, according to the
World Health Organization.
Symptoms of Depression
According to
the DSM-IV-TR criteria for diagnosing a
major
depressive disorder one or both of the
following two depression symptoms need to be
present:
- Depressed
mood, or
- Loss of
interest or pleasure.
It is enough
to have either of these above depression
symptoms in conjunction with four of the
following:
Feelings of
overwhelming sadness or fear, or seeming
inability to feel emotion.
Marked
decrease of interest in pleasurable
activities.
Changing
appetite and marked weight gain or
weight
loss.
Disturbed
sleep patterns, either insomnia or sleeping
more than normal.
Changes in
activity levels, restless or moving
significantly slower than normal.
Fatigue,
both mental and physical.
Feelings of
guilt, helplessness,
anxiety, and/or fear.
Lowered
self-esteem.
Decreased
ability to concentrate or make decisions.
Thinking
about death or suicide.
Depression in
children is not as obvious as it is in
adults; depression symptoms children
demonstrate include:
- Loss of
appetite.
- Sleep
problems such as nightmares.
- Problems
with behavior or grades at school where
none existed before.
-
Significant behavioral changes; becoming
withdrawn, sulky, aggressive.
In older
children and adolescents, an additional
indicator may be the use of drugs or
alcohol. Moreover, depressed adolescents are
at risk for further destructive behaviours,
such as eating disorders and self-harm.
One of the
most widely used instruments for measuring
depression severity is the Beck Depression
Inventory, a 21 question multiple choice
survey.
It is hard
for people who have not experienced
clinical
depression, either personally or by regular
exposure to people suffering it, to
understand its emotional impact and
severity, interpreting it instead as being
similar to "having the blues" or "feeling
down". As the list of symptoms above
indicates, clinical depression is a syndrome
of interlocking symptoms which goes far
beyond sad or painful feelings.
A variety of
biological indicators, including measurement
of neurotransmitter levels, have shown that
there are significant changes in brain
chemistry and an overall reduction in brain
activity. One consequence of a lack of
understanding of its nature is that
depressed individuals are often criticized
by themselves and others for not making an
effort to help themselves. However, the very
nature of depression alters the way people
think and react to situations to the point
where they may become so pessimistic that
they can do little or nothing about their
condition. Because of this profound and
often overwhelmingly negative outlook, it is
imperative that the depressed individual
seek professional help. Untreated depression
is typically characterized by progressively
worsening episodes separated by plateaus of
temporary stability or remission. If left
untreated it will generally resolve within
six months to two years although
occasionally depression becomes
chronic and lasts for many years or
indefinitely. In many cases (but not all)
treatment can shorten the period of distress
to a matter of weeks. While depressed,
the person may damage themselves socially
(e.g. the break up of relationships),
occupationally (e.g. loss of a job),
financially and physically. Treatment of
depression can significantly
reduce the incidence of this damage,
including reducing the risk of suicide which
is otherwise a common and tragic outcome.
For all of these reasons, treatment of
clinical
depression is seen by many as very
useful and at times life saving.
Some people can experience anhedonia for
long periods of time before they discover it
is a mental illness. The inability to feel
pleasure can advance negativity already
present in a depressed person's mental
state.
Types of
major clinical
depression
(separated
out by
symptoms)
Major depression is also referred to as
major depressive disorder or biochemical,
clinical, endogenous, unbipolar, or
biological depression. It is characterized
by a severely depressed mood that persists
for at least two weeks. Episodes of
depression may start suddenly or slowly and
can occur several times through a person's
life. Major depressive disorder may be
categorized as "single episode" or
"recurrent" depending on whether previous
episodes have been experienced before.
Clinicians recognise several subtypes of
major depression.
- Psychotic
depression is accompanied by
hallucinations or delusions.
- Melancholic
depression (what used to
be referred to as endogenous depression)
is characterized by insomnia, poor
appetite and weight loss, less responsive
mood, and morning worsening.
- Atypical
depression is characterized
by "reversed vegetative symptoms" which
include oversleeping, overeating, leaden
paralysis, rejection sensitivity and
temporary brightening of mood in response
to positive events. It may overlap with
anxiety and
panic attacks. It is often
more chronic than melancholic
depression.
- Dysthymia is a long-term, mild
depression that lasts for at least two
years. By definition the symptoms are not
as severe as in major depression, although
those with dysthymia are highly likely to
have superimposed major depressive
episodes (known as "double
depression").
It often begins in adolescence and spans
several decades.
Major depression may also be referred to
as unipolar affective disorder, a term which
emphasizes its relatedness to bipolar
disorder.
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