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Known Carcinogens| What are carcinogens?
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Carcinogenic Substances

What is a Carcinogen?

Dorland's Illustrated Medical Dictionary (23rd Edition) describes a carcinogen as "any cancer-producing substance". 

The Merck Manual of Diagnosis and Therapy (14th Edition, 1982) - which provides useful information to physicians, medical students and other health professionals - defines a carcinogen as "a chemical or physical agent that has the potential of producing neoplasia (i.e. formation of any new and abnormal growth)".

Science - and research - based educational institutions in the US (like the Texas A&M University) consider a chemical to be a carcinogen if:

  • it has been evaluated by the WHO's International Agency for Research on Cancer (IARC) and found to be a carcinogen or potential carcinogen;

  • it is listed as a carcinogen or potential carcinogen in the Annual Report on Carcinogens published by the US National Toxicology Program (NTP); or if

  • it is regulated by the US Occupational Safety and Health Administration (OSHA) as a carcinogen. 

(The IARC coordinated and conducts research on the causes of human cancer and develops scientific strategies for cancer control while the NTP is part of the US Department of Health & Human Services, which provides information about potentially toxic chemicals to US regulatory and research agencies and the public.)

Carcinogens / Cancer-causing Chemicals in Cosmetics & Daily Use Products

In an exhaustive market survey and random label analysis of 120 cosmetics and daily use products, all are found to be containing at least one or more of the following:

  • ingredients which are known human carcinogens (cancer-causing agents);
  • substances which may be contaminated with carcinogenic (cancer-causing) by products;
  • substances that can react with other chemicals to form potent carcinogens during storage and use; or
  • chemicals which are suspected human carcinogens or which have been linked to cancer in animal tests.

The research found at least 60 known or suspected carcinogenic chemicals that can be commonly found in cosmetic products. A quick check of the ingredient declarations stated on these120 products that were surveyed found at least 50 such chemicals to be present or are likely to be present.

What is shocking is that all the categories of cosmetics (eg; eye shadows, eyebrow pencils, eyeliners, mascara, foundation, nail plish, makeup removers, toners, compact and loose powder etc.), personal care products (eg; hair gels and sprays, fragrances, antiperspirants and deodorants, and sunscreens etc.) and daily use items (eg; toothpaste, mouthwash, soaps and shower creams, shampoos, and conditioners etc.) that were checked are potentially carcinogenic.

Human Carcinogens

Among the carcinogenic (and potentially carcinogenic) chemicals found in the label check are mineral oil, coal tar ingredients (i.e. phenylenediamines, synthetic colors and saccharin), benzene derivatives (chemicals labeled as just "fragrance" on products) and talc are identified as human carcinogens.

Sun-treated and mildly treated mineral oils, coal tar, benzene and talc containing asbestiform fibers are 4 of 70 chemicals classified as Group 1 Carcinogens, i.e. "materials known to be carcinogenic to humans", by the World Health Organization's International Agency for Research on Cancer (IARC). 

  • A total of 23 products contained mineral oil. They range from baby lotions and face creams to eye shadows and hair conditioners. (This does not include 5 samples with petrolatum, better described as a "mineral oil jelly", which exhibits many of the same harmful properties as mineral oil, and should thus be treated with the same caution.)
  • Coal tar ingredients turned up on the labels of at least 71 products that we checked. They range from lipsticks and eye shadows to face crams and perfumes. Of these 120, 66 had either one or more of 4 notorious synthetic colors - FD&C Blue No.1 (in 20 products), FD&C Yellow No.5 (25 products), FD&C Yellow No.6 (9 products) and D&C Red No.33 (12 products). FD&C Blue No.1 is a know carcinogen. As for FD&C Yellow No.5 and No.6, and D&C Red No.33, impurities found in commercial batches of these colors have been shown to cause cancer not only when ingested, but also when applied to the skin. Some artificial coal tar colors also contain heavy metal impurities, including arsenic and lead, which are carcinogenic.
  • Phenylenediamines turned up in at least 3 products - all hair dyes.
  • Saccharin, a synthetic compound derived form coal tar, and artificial sweetener that has been proven to cause bladder cancer in animal studies, turned up in 2toothpastes that were checked. Saccharin can also promote the cancer-causing effects of other carcinogens.
  • "Fragrance" was found in a whopping 68 products - ranging from baby lotions and baths to face creams and cleansers, deodorants, shaving creams, shampoos and conditioners. ontrary to what its name implies, the word "fragrance" does not denote just one ingredient. Fragrances used in cosmetics are derived from mixtures of 600 or more raw materials and synthetic chemicals. According to the 1986 Report by the Committee on Science & Technology of the US house of Representatives, some 95% of chemicals used in fragrances are synthetic compounds derived from petroleum. Some of the compounds could thus include benzene derivatives which are known to be present in petroleum. Carcinogenic fragrance chemicals can be absorbed through the skin. Fro example, one widely used fragrance throughout the 1970s, acetylethyltetramethyltetralin (AETT) was shown in animal tests to be readily absorbed through the skin. The chemical not only dyed the inner organs of test animals blue, but also damaged the brain and spinal cord. It was banned only after products containing it have been widely distributed and used by consumers for many years.
  • Talc was listed on 12 products checked in the survey. cosmetic talc is reportedly carcinogenic as it can be contaminated with asbestos fibers, which can be inhaled when applying makeup. (There is no safe level for asbestos exposure.) clear evidence exist that inhaling talc and using it in the genital area causes ovarian cancer. Asbestos is also known to be a concarcinogen, i.e. it can potentiate the activity of substances that cause cancer.
Regulated Carcinogens

Besides the above, a total of 34 products are found to contain formaldehyde; and ingredients like 2-bromo-2-nitropropane, 1, 3-diol (also known as BNPD or Bronopol), urea, diazolidinyl urea, imidazolidinyl urea, DMDM hydantoin and Quaternium-15 -- all of which either contain formaldehyde, may release formaldehyde, or may break down into formaldehyde. Formaldehyde is a carcinogen and neurotoxin. It is regulated by the US Occupational Safety and Health Administration (OSHA) as a carcinogen, and is one of 57 chemicals in the IARC's Group 2A list of substances that are "probably carcinogenic to humans".

Mutagenic & Potentially Carcinogenic Chemicals

Also sodium lauryl sulfate (SLS) and the alcohol form of SLS, sodium laureth sulfate (SLES) were found in a total of 17 samples.

Japanese studies have found SLS to be a mutagen. According to toxicologists, any chemical capable of causing mutations is likely to increase the risk of cancer. Alone the chemical is harmful enough. But it can also react with other chemicals used in cosmetics to form nitrates. Nitrates are known cancer-causing agents.

According to experts, once nitrates have formed, they can enter the bloodstream in large numbers from shampooing, and from using bubble bath, shower gels and facial cleansers.

SLS and SLES are reportedly the only known cleansing agents in shampoos and cleaners to enter the blood system.

Carcinogenic Cosmetics Long Known

The toxicity and cancer-causing potential of many ingredients used in cosmetics and personal care products have long been know.

  • for example, the US FDA has known since 1979 that cosmetics may be contaminated with cancer-causing nitrosamines. In the 1970s it published a notice in the Federal Register which urged the cosmetics industry to remove nitrosamines (namely nitrosodiethanolamine, in short NDELA) from cosmetics. Although the industry has made some progress by using higher quality control standards in its selection of raw materials, an FDA report from the late 1980s noted that some 37% of the products tested still contained carcinogenic nitrosamine impurities. (Note: According to some reports, cosmetics are the second source of cancer-causing nitrosamines, after tobacco.)
  • According to researcher-lecturer Debra Lynn Dadd in her 1986book, the Nontoxic Home, "an investigation done by Consume Reports magazine (published by the US Consumers' union) revealed about 20 different chemicals used regularly in hair coloring products that are potential human carcinogens".
  • In 1989, a house subcommittee asked the US OSHA (Occupational Safety and Health Administration) to analyze 2,983 chemicals used in personal care products. The results were as follows; 884 of the ingredients were found to be toxic. Of these, 778 can cause acute toxicity, 146 can cause tumors, 218 can cause reproductive complications, 314 can cause biological mutation, and 376 can cause skin and eye irritations.
  • More recently, the Boston Globe reported that the US General Accounting Office (a nonpartisan agency within the legislative branch of the US government) has identified more than 125 cosmetic ingredients suspected of causing cancer-- and others that may cause birth defects.

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